The 'Rehab' singer – who flew out to Jamaica to work on her much-anticipated third album earlier this week – has given two of her beloved pets to goddaughter Dionne Bromfield and called an animal shelter asking them to pick up the others from her London home.
A source told The Sun newspaper: "Amy was pretty upset about it because she loved them dearly, but she had to give them up.
"They were climbing all over the place, breeding and generally getting out of control."
Although Amy has got rid of her cats, she won't be short of company when she returns to the UK as she is believed to be planning a reconciliation with ex-husband Blake Fielder-Civil.
The 26-year-old star is reportedly arranging flights for Blake - who was released from jail last February after serving time for grievous bodily harm (GBH) and attempting to pervert the course of justice – to join her when he completes his drug treatment programme.
A source said: "Amy and Blake want to spend some time together away from home where they have been governed by his curfew.
"She is desperate for him to join her and, of course, he wants a nice holiday and some fun. Friends have tried talking her out of it - but at the moment she's more focused on work than she has been for ages."