In the flick Portman, 29, plays a woman who tries to have a sexual relationship with a male friend without getting romantically attached.
But Kutcher, 32, told British newspaper the Sunday Mirror it wasn't quite as good as you would expect.
He said: 'I was shooting so many sex scenes I was getting tired of it. I never thought that anything related to sex would be something I'd get tired of.'
Demi Moore's husband even suggested that shooting the scenes was quite tough.
He added: 'The director would come back and say, 'I think you need to orgasm sooner'. So your male machismo is like, 'No, no, no. It would take me much longer than this.'
'I'm sure that every actor says it, but it's always slightly more complicated than it is in real life.'