The band recently performed a show at the Roundhouse in London and footage of the gig appeared online soon after.
According to GigWise, Grohl was seen getting angry during the fight when someone in the audience started a fight.
He said: 'You don't f***ing fight at my show you a**hole. Let me see him, who's fighting right now? It's that guy in the stripped shirt. Hey motherf****er look at me, get the f**k out of my show right now.'
Grohl added: 'You don't come to my show and fight. You come to my show and dance you a**hole. I don't put up with that bulls**t - you people came here to have a good time and that guy can f**k off.'