50 Cent "disgusted" a girl when he accidently misspelt Justin Bieber's name.
The 39-year-old rapper is an avid user of social media and has over seven million followers on Twitter.
He's often tweeted about the pop star, and in 2010 he warned Justin's fans to stop following him, writing: "I don't have anything against Justin Beiber he's a baby. U people on here are so full of hate u try to make trouble. I still wish u lucK (sic)".
But rather than the singer's loyal admirers getting upset over the comments made, they lashed out at his typo instead.
"Don't be putting Bieber up against me. That's the Bieber section. Let me tell you something: It's not OK to directly say anything negative about Bieber. His fans will not accept your apology," 50 explained to New York Daily News' Confidenti@l.
"By accident I misspelled his name [on Twitter]; I switched the 'i' and the 'e.' Have you ever had a 12-year-old girl angry with you? Just totally disgusted with me. Since then he's been arrested... Bieber's been through some phases in front of us. We have to at least understand the teenage process. It's a part of growing up."
50 was speaking about the popstar after being quizzed on his new underwear line Frigo. Justin recently stripped off to his boxers as the face of Calvin Klein; but that's not something the rapper would do.
While he admits he got into trouble as a youngster, 50 insists the difference between his troubles and Justin's is that no one paid attention to his antics at the time.
The star also touched upon some of his celebrity crushes, naming Black Swan beauty Natalie Portman as one.
"This is a different kind of sexy," 50 gushed. "She looks completely innocent, like she's going to do some freaky stuff to you."