The actor is said to have gone missing at posh eatery Daniel in Manhattan just hours before his meltdown.
And when an aide went to look for the troubled Two And A Half Men star, he found him nude in the toilet.
'When the assistant opened the door, there was Charlie standing there naked with cocaine all over his face.
'He was delusional and just completely lost. Totally out of it,' a source said.
'The assistant helped Charlie get dressed in the bathroom,' the source told celebrity news website, RadarOnline.com.
'Charlie was out of it. Gone. Just wasted. At that point the assistant steered him out of there and back to the hotel and the rest of the party came along.'
Sheen, 45, had been at the French restaurant with several pals, including porn star Capri Anderson, who was later found naked in his suite at the Plaza Hotel.
Cops were called to the Fifth Avenue hotel early on Tuesday morning after Sheen allegedly went ballistic and caused $7,000 USD worth of damage.
Sheen's spokesman said he had no comment on the report.