Lily Allen once performed live despite having chronic diarrhoea.
The 'It's Not Fair' singer's worst on-stage experience was when she fell ill with a stomach bug during a show in the US.
However, Lily was so desperate not to disappoint fans she refused to go backstage and visit a bathroom until she had finished the full set.
She explained to Q magazine: "The worst was being on stage in Seattle two years ago and I came down with diarrhoea but I still went on. I was desperate for a poo the whole way through. At the end of the show I went to the toilet and it would not stop.
"The crowd were going, 'Lily! Lily!', for an encore. I didn't feel I could send anyone out and say, 'Will you lot shut up, she's having a c**p', but that was the truth."
Lily is not the only musician to suffer from an upset stomach during a show.
Green Day bassist Mike Dirnt was so unwell during a concert at the Giants Stadium in New Jersey – which seats 80,000 people – he soiled himself on stage.
He revealed: "I had stomach flu or something, I came down from a jump and was like, 'That's not good!' I was throwing up before I went on."
After the smelly mishap a bucket was placed at the side of the stage which Mike used as a toilet seven times during the show.