The new movie is being directed by David Frankel, who Streep worked with on the film The Devil Wears Prada, for Sony Pictures.
According to Variety, Streep and Jones will play a couple who have been married a long time and are struggling with getting intimate together.
They then spend a week having marriage and sex therapy from a well-known relationship guru, who will be played by Steve Carell.
The movie will start production in August this year and is set to be distributed by Sony in North America next year.