The 41 year-old claimed that the Best Thing I Never Had singer has inspired him in the same way the King of Pop did before his death in 2009.
In an interview with Miami radio station 99 Jamz, Jay-Z said that Beyonce, 29, is the 'second coming of Michael Jackson'.
The rap mogul said: 'What I've learnt from her is similar to what I learnt from [Michael Jackson] - and I know that's blasphemy to compare the two because Mike was such an innovator, but I think she's like the second coming.'
He added: 'The hard work and dedication that she puts into her shows, it just makes you want to work harder at your own craft. She's like a machine.'