The A-list couple have been linked to roles in a Hollywood version of the hit Broadway musical Rock of Ages.
It has been reported that Perry, 26, could play an exotic dancer in the flick, which also stars Tom Cruise.
Brand's role in the movie is not yet known but film producers are believed to think he would want to star opposite his wife.
A source told British newspaper the Daily Star: 'Once we knew we had Russell's interest we suggested that Katy might like to appear in the film as well, and she said she would love to. The contracts are being drawn up now but we are confident that once shooting starts in Miami in May that she will drop by in between her Teenage Dream tour.'