Gaga, 25, real name Stefani Germanotta, has previously admitted she is a fan of KISS and guitarist Paul Stanley is keen for them to team up on a record.
In a recent interview with LA Weekly, Stanley, 59, said: 'Anything's possible. She's terrific, and it's not improbable,' when asked if there would be a chance of KISS and Gaga collaboration in the future.
Similar to the You and I singer, Paul says one of the keys to the group's success has been their dedication to putting on a big show.
He added: 'We ultimately have always seen ourselves as a live band that prides itself not only in playing music but in entertaining. And I say 'entertainment' in capital letters with lights flashing around it. We're proud of that.
'There's nothing worse than going to a concert and paying for a high-priced ticket and seeing somebody stroll out onto stage and sit on a stool. You kind of wonder where your money went.'