The Girls Aloud star was already a hit judge on the British version of the talent competition when Simon Cowell asked her to have a seat on the new panel as he took the series to the US earlier this year.
But the 28-year-old failed to impress bosses at Fox and was axed from the judging panel, only to be replaced by Nicole Scherzinger.
Now Cheryl is said to be in 'advanced talks' to play a talent show judge who assesses Cameron's character in the upcoming flick.
A source told British newspaper the Daily Mail: 'This is a bit of fun for Cheryl. She will film the scenes imminently and is really looking forward to it.
'It doesn't mean she suddenly wants to become an actress. It was just an opportunity that has come up while she has been having some down time and she thought it would be great fun to take part.'
Cole is said to have impressed film executives during an appearance at the Cannes Film Festival earlier this year.
What to Expect When You're Expecting tells the story of six different couples who are each preparing to welcome a child.
The movie is set to be released in May 2012.